【Original Papers and Review Articles】

Quantitative live-cell imaging of secretion activity reveals dynamic immune responses

Mai Yamagishi, Kaede Miyata, Takashi Kamatani, Hiroki Kabata, Rie Baba, Yumiko Tanaka, Nobutake Suzuki
Masako Matsusaka, Yasutaka Motomura, Tsuyoshi Kiniwa, Satoshi Koga, Keisuke Goda, Osamu Ohara
Takashi Funatsu, Koichi Fukunaga, Kazuyo Moro, Sotaro Uemura, Yoshitaka Shirasaki

iScience, 27(6), 109840 (2024)

Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation

Yumiko Tanaka, Mai Yamagishi, Yasutaka Motomura, Takashi Kamatani, Yusuke Oguchi, Nobutake Suzuki, Tsuyoshi Kiniwa, Hiroki Kabata, Misato Irie, Tatsuhiko Tsunoda, Fuyuki Miya, Keisuke Goda, Osamu Ohara, Takashi Funatsu, Koichi Fukunaga, Kazuyo Moro, Sotaro Uemura, Yoshitaka Shirasaki

Communications Biology, 6, 915 (2023)

Upregulation of IL-4 receptor signaling pathway in circulating ILC2s from asthma patients

Rie Baba, Hiroki Kabata, Yoshitaka Shirasaki, Takashi Kamatani, Mai Yamagishi, Misato Irie, Risa Watanabe, Masako Matsusaka, Katsunori Masaki, Jun Miyata, Kazuyo Moro, Sotaro Uemura, Koichi Fukunaga

Journal of Allergy and Clinical Immunology, 1(4), 299-304 (2022)

Live-Cell Imaging Technique to Visualize DAMPs Release During Regulated Cell Death.

Mai Yamagishi, Yoshitaka Shirasaki

Methods in molecular biology, 2274, 337-352 (2021)

Microfluidic Immunoassays for Time-Resolved Measurement of Protein Secretion from Single Cells.

Mai Yamagishi, Osamu Ohara, Yoshitaka Shirasaki

Annual review of analytical chemistry,13(1) ,67-84 (2020)

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.

Apostolos Polykratis, Arne Martens, Remzi Onur Eren, Yoshitaka Shirasaki, Mai Yamagishi, Yoshifumi Yamaguchi, Sotaro Uemura, Masayuki Miura, Bernhard Holzmann, George Kollias, Marietta Armaka, Geert van Loo, Manolis Pasparakis

Nature cell biology, 21(6), 731-742 (2019)

A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs.

Shin Murai, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Mai Yamagishi, Ryodai Shindo, Joanne M Hildebrand, Ryosuke Miura, Osamu Nakabayashi, Mamoru Totsuka. Taichiro Tomida, Satomi Adachi-Akahane, Sotaro Uemura, John Silke, Hideo Yagita, Masayuki Miura, Hiroyasu Nakano

Nature communications, 9(1) , 4457 (2018)

Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response.

Ting Liu, Yoshifumi Yamaguchi, Yoshitaka Shirasaki, Koichi Shikada, Mai Yamagishi, Katsuaki Hoshino, Tsuneyasu Kaisho, Kiwamu Takemoto, Toshihiko Suzuki, Erina Kuranaga, Osamu Ohara, Masayuki Miura

Cell reports, 8(4), 974-82 (2014)

Real-time single-cell imaging of protein secretion.

Yoshitaka Shirasaki, Mai Yamagishi, Nobutake Suzuki, Kazushi Izawa, Asahi Nakahara, Jun Mizuno, Shuichi Shoji, Toshio Heike, Yoshie Harada, Ryuta Nishikomori, Osamu Ohara

Scientific reports, 4, 4736 (2014)

【Japanese Review】

【Systems Clinical Immunology】Omics Analysis of Cellular Societies in Research on Hereditary Immune Diseases

小原收, 川島祐介, 山岸舞, 白崎善隆

炎症と免疫, 27(5), 412-416 (2019)

Systems Clinical Immunology Approach: Omics Analysis of Cellular Societies in Research on Inherited Immune Diseases

小原收, 川島祐介, 山岸舞, 白崎善隆

日本臨床免疫学会総会プログラム抄録集, 46, 57 (2018)

Next-Generation Molecular Measurement Technology Required for Humoral Diagnosis: Application of Single-Cell Secretion Real-Time Imaging to Humoral Diagnosis

白崎善隆, 山岸舞, 鈴木信勇, 宮田楓, 田中優実子, 小原收, 上村想太郎

生命科学系学会合同年次大会, 2017年度, 2AW06-4 (2017)

Single-cell secretion real-time imaging

白崎善隆, 山岸舞, 小原收, 上村想太郎